Product Detail
Product NameTRIM29 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsWB IHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total TRIM29 protein.
Immunogen TypeRecombinant Protein
Immunogen DescFusion protein corresponding to residues near the N terminal of human tripartite motif containing 29
Target NameTRIM29
ConjugateUnconjugated
Other NamesATDC
Accession NoSwiss-Prot#: Q14134
NCBI Gene ID: 23650
Gene Accssion: BC017352
Uniprot
Q14134
Gene ID
23650;
Sdspage MW66kd
Concentration2.2mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Gel: 8%SDS-PAGE
Lysate: 40ug HT-29 cell
Primary antibody: 1/400 dilution
Secondary antibody dilution: 1/8000
Exposure time: 10 seconds
Immunohistochemical analysis of paraffin-embedded Human brain tissue using #35641 at dilution 1/50.
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.
If you have published an article using product 35641, please notify us so that we can cite your literature.
et al,Upregulated expression of ACTL8 contributes to Invasion and metastasis and indicates poor prognosis In colorectal cancer. In Onco Targets Ther on 2019 Mar 1 by Han Q, Sun ML, et al.. PMID: 30881029
, (2019),
PMID:
30881029
et al,Transcriptional dysregulation of TRIM29 promotes colorectal cancer carcinogenesis via pyruvate kinase-mediated glucose metabolism. In Aging (Albany NY) on 2021 Jan 20 by Jing Han, Zitong Zhao, et al..PMID:33495406
, (2021),
PMID:
33495406
et al,TRIM29 is differentially expressed in colorectal cancers of different primary locations and affects survival by regulating tumor immunity
based on retrospective study and bioinformatics analysis. In J Gastrointest Oncol on 2022 Jun by Jing Han, Jing Zuo,et al..PMID:35837175
, (2022),
PMID:
35837175
Yes
