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ERBB4 Antibody#35681

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Product Detail

Product NameERBB4 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntigen affinity purification.

ApplicationsWB IHC

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous levels of total ERBB4 protein.

Immunogen TypeRecombinant Protein

Immunogen DescFusion protein corresponding to a region derived from internal residues of human v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Target NameERBB4

ConjugateUnconjugated

Other NamesHER4; ALS19; p180erbB4

Accession NoSwiss-Prot#: Q15303
NCBI Gene ID: 2066
Gene Accssion: BC112199/Q15303

Uniprot Q15303

Gene ID 2066;

Sdspage MW147kd

Concentration1.7mg/ml

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C

Application Details

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Gel: 6%SDS-PAGE
Lysate: 40ug Hela cell
Primary antibody: 1/200 dilution
Secondary antibody dilution: 1/8000
Exposure time: 5 seconds
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #35681 at dilution 1/40.

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.?

If you have published an article using product 35681, please notify us so that we can cite your literature.

et al,MicroRNA锟?46b, a sensitive indicator of mesenchymal stem cell repair of acute renal injury.In Stem Cells Transl Med on 2016 Oct by Yuan Zhu, Jing Yu et al..PMID:27400799 , (2016),
PMID: 27400799
et al,MicroRNA-146b, a sensitive indicator of mesenchymal stem cell repair of acute renal injury. In Stem Cells Transl Med on 2016 Oct by Yuan Zhu, Jing Yu, et al..PMID: 27400799 , (2016),
PMID: 27400799
et al,The Notch1/Hes1 pathway regulates Neuregulin 1/ErbB4 and participates in microglial activation in rats with VPA-induced autism. In Prog Neuropsychopharmacol Biol Psychiatry on 2024 Apr 20 by Yanan Deng, Liping Ma, et al..PMID:38242426 , (2024),
PMID: 38242426

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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