Product Detail
Product NameMAGEA10 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsWB IHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total MAGEA10 protein.
Immunogen TypeRecombinant Protein
Immunogen DescFusion protein corresponding to a region derived from internal residues of human melanoma antigen family A, 10
Target NameMAGEA10
ConjugateUnconjugated
Other NamesCT1.10; MAGE10
Accession NoSwiss-Prot#: P43363
NCBI Gene ID: 4109
Gene Accssion: BC004105/P43363
Uniprot
P43363
Gene ID
4109;
Sdspage MW41kd
Concentration2.3mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200
Gel: 8%SDS-PAGE
Lysate: 40ug A375 cell
Primary antibody: 1/400 dilution
Secondary antibody dilution: 1/8000
Exposure time: 20 seconds
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #36594 at dilution 1/50.
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants.?
If you have published an article using product 36594, please notify us so that we can cite your literature.
et al,Establishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer.In Cancer Manag Res.On 2018 Jul 16 by Jin S, Cao S et al..PMID: 30038519
, (2018),
PMID:
30038519
Yes
