Product Detail
Product NameOS9 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsWB
Species ReactivityHu Ms
SpecificityThe antibody detects endogenous levels of total OS9 protein.
Immunogen TypeRecombinant Protein
Immunogen DescFusion protein corresponding to a region derived from internal residues of human osteosarcoma amplified 9, endoplasmic reticulum lectin
Target NameOS9
ConjugateUnconjugated
Other NamesOS-9; ERLEC2
Accession NoSwiss-Prot#: Q13438
NCBI Gene ID: 10956
Gene Accssion: BC007254
Uniprot
Q13438
Gene ID
10956;
Sdspage MW76kd
Concentration2.4mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:500-1:2000
Gel: 6%SDS-PAGE
Lysates (from left to right): K562 and NIH/3T3 cell
Amount of lysate: 40ug per lane
Primary antibody: 1/200 dilution
Secondary antibody dilution: 1/8000
Exposure time: 3 minutes
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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et al,Peroxiredoxin 4 deficiency induces accelerated ovarian aging through destroyed proteostasis in granulosa cells. In Biochim Biophys Acta Mol Basis Dis on 2024 Oct by Xiaofei Zou, Xiuru Liang et al..PMID:38971505
, (2024),
PMID:
38971505