Product Detail
Product NameMAGEA3 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsWB IHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total MAGEA3 protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide corresponding to residues near the C terminal of human melanoma antigen family A, 3
Target NameMAGEA3
ConjugateUnconjugated
Other NamesHIP8; HYPD; CT1.3; MAGE3; MAGEA6
Accession NoSwiss-Prot#: P43357
NCBI Gene ID: 4102
Gene Accssion: NP_005353/P43357
Uniprot
P43357
Gene ID
4102;
Sdspage MW35kd
Concentration2.9mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Gel: 10%SDS-PAGE
Lysates (from left to right): Human testis tissue, A549 and PC3 cell
Amount of lysate: 40ug per lane
Primary antibody: 1/400 dilution
Secondary antibody dilution: 1/8000
Exposure time: 2 minutes
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using #37138 at dilution 1/50.
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
If you have published an article using product 37138, please notify us so that we can cite your literature.
et al,Establishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer.In Cancer Manag Res.On 2018 Jul 16 by Jin S, Cao S et al..PMID: 30038519
, (2018),
PMID:
30038519