Product Detail
Product NameITGA6 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsIHC
Species ReactivityHu Ms
SpecificityThe antibody detects endogenous levels of total ITGA6 protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide corresponding to a region derived from internal residues of human integrin, alpha 6
Target NameITGA6
ConjugateUnconjugated
Other NamesCD49f; VLA-6; ITGA6B
Accession NoSwiss-Prot#: P23229
NCBI Gene ID: 3655
Gene Accssion: NP_000201
Uniprot
P23229
Gene ID
3655;
Concentration1.7mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37155 at dilution 1/50.
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
If you have published an article using product 37155, please notify us so that we can cite your literature.
et al,Increased Expression of Integrin Alpha 6 in Nucleus Pulposus Cells in Response to High Oxygen Tension Protects against Intervertebral Disc Degeneration
, (2021),
PMID:
34707783
Yes
