Product Detail
Product NamePIK3C3 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsIHC
Species ReactivityHu Ms Rt
SpecificityThe antibody detects endogenous levels of total PIK3C3 protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide corresponding to a region derived from internal residues of human phosphatidylinositol 3-kinase, catalytic subunit type 3
Target NamePIK3C3
ConjugateUnconjugated
Other NamesVPS34; hVps34
Accession NoSwiss-Prot#: Q8NEB9
NCBI Gene ID: 5289
Gene Accssion: NP_002638
Uniprot
Q8NEB9
Gene ID
5289;
Concentration1.5mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #37356 at dilution 1/40.
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37356 at dilution 1/40.
Phosphatidylinositol 3-kinase catalytic subunit type 3?is an?enzyme?that in humans is encoded by thePIK3C3?gene. PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation.
If you have published an article using product 37356, please notify us so that we can cite your literature.
et al,CSF-1R regulates non-small cell lung cancer cells dissemination through Wnt3a signaling.
, (2017),
PMID:
29218239
Yes
