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Location： Home > Polyclonal Antibodies > PKMYT1 Antibody

PKMYT1 Antibody#37829

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Product Detail

Product NamePKMYT1 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntigen affinity purification.

ApplicationsWB IHC

Species ReactivityHu Ms

SpecificityThe antibody detects endogenous levels of total PKMYT1 protein.

Immunogen TypePeptide

Immunogen DescSynthetic peptide corresponding to a region derived from internal residues of human protein kinase, membrane associated tyrosine/threonine 1

Target NamePKMYT1

ConjugateUnconjugated

Other NamesMYT1; PPP1R126

Accession NoSwiss-Prot#: Q99640
NCBI Gene ID: 9088
Gene Accssion: NP_004194 /Q99640

Uniprot Q99640

Gene ID 9088;

Sdspage MW55kd

Concentration0.8mg/ml

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C

Application Details

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:50

Gel: 8%SDS-PAGELysate: 40 μgLane: A375 cell lysatePrimary antibody: PKMYT1 Antibody at dilution 1/200Secondary antibody: Goat anti rabbit IgG at 1/5000 dilutionExposure time: 5 minutes
The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using PKMYT1 Antibody at dilution 1/35. (Original magnification: ×200).

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

If you have published an article using product 37829, please notify us so that we can cite your literature.

et al,PKMYT1 is associated with prostate cancer malignancy and may serve as a therapeutic target.In Gene on 2020 Mar 29 by Wang J, Wang L, et al..PMID:32234541 , (2020),
PMID: 32234541

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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