Product Detail
Product NameFASN antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total FASN protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant fusion protein of human Fatty Acid Synthase (FASN) (NP_004095.4).
Target NameFASN
ConjugateUnconjugated
Other NamesFAS;OA-519;SDR27X1;FASN
Accession NoUniprot:P49327
GeneID:2194
Uniprot
P49327
Gene ID
2194
Sdspage MW273KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human breast cancer using Fatty Acid Synthase (FASN) antibody.
Western blot analysis of extracts of various cell lines, using Fatty Acid Synthase (FASN) antibody.
Immunofluorescence analysis of C6 cells using Fatty Acid Synthase (FASN) Rabbit pAb.
Immunofluorescence analysis of NIH/3T3 cells using Fatty Acid Synthase (FASN) Rabbit pAb.
Immunofluorescence analysis of U2OS cells using Fatty Acid Synthase (FASN) Rabbit pAb.
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
If you have published an article using product 38133, please notify us so that we can cite your literature.
et al,Hepatoprotective effects of Xiaoyao San formula on hepatic steatosis and inflammation via regulating the sex hormones metabolism. In World J Hepatol on 2024 Jul 27 by Xiao-Li Mei , Shu-Yi Wu ,et al..PMID:39086531
, (2024),
PMID:
39086531