Product Detail
Product NameALPL antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total ALPL protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant fusion protein of human Alkaline Phosphatase (Alkaline Phosphatase (ALPL)) (NP_000469.3).
Target NameALPL
ConjugateUnconjugated
Other NamesALPL;AP-TNAP;APTNAP;HOPS;TNAP
Accession NoUniprot:P05186
GeneID:249
Uniprot
P05186
Gene ID
249
Sdspage MW80KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human colon carcinoma using Alkaline Phosphatase (ALPL) Rabbit pAb.
Western blot analysis of extracts of various cell lines, using Alkaline Phosphatase (ALPL) antibody.
Immunohistochemistry of paraffin-embedded human lung cancer using Alkaline Phosphatase (ALPL) Rabbit pAb.
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.
If you have published an article using product 38179, please notify us so that we can cite your literature.
et al,Surface mIneralized biphasic calcium phosphate ceramics loaded with urIne-derived stem cells are effective In bone regeneration. In J Orthop Surg Res on 2019 Dec 9 by XIng , Li L, et al..PMID:31818319
, (2019),
PMID:
31818319
The lead time is currently 2 weeks.
