Product Detail
Product NameCOL2A1 antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse
SpecificityThe antibody detects endogenous level of total COL2A1 protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant fusion protein of human COL2A1 (NP_149162.2).
Target NameCOL2A1
ConjugateUnconjugated
Other NamesCOL2A1;ANFH;AOM;COL11A3;SEDC;STL1
Accession NoUniprot:P02458
GeneID:1280
Uniprot
P02458
Gene ID
1280
Sdspage MW141kDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded Human breast cancer using COL2A1 Rabbit pAb.
Western blot analysis of extracts of mouse liver, using COL2A1 antibody.
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
If you have published an article using product 38254, please notify us so that we can cite your literature.
et al,Blocking ACSL6 Compromises Autophagy via FLI1‐Mediated Downregulation of COLs to Radiosensitize Lung Cancer. In Adv Sci (Weinh) on 2024 Oct by Wen Ding, Shijun Bao,et al..PMID:39206814
, (2024),
PMID:
39206814
The lead time is currently 2 weeks.
