Product Detail
Product NamePTPRA antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were purified by affinity purification using immunogen.
ApplicationsWB,IHC
Species ReactivityHuman,Mouse
SpecificityThe antibody detects endogenous level of total PTPRA protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant protein of human PTPRA.
Target NamePTPRA
ConjugateUnconjugated
Other NamesLRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha;
Accession NoSwiss-Prot#: P18433
NCBI Gene ID: 5786
Uniprot
P18433
Gene ID
5786;
Sdspage MW90kd
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
WB 1:500 - 1:2000
IHC 1:100 - 1:200
Western blot analysis of extracts of various cell lines, using PTPRA at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human colon using PTPRA at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human kidney using PTPRA at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using PTPRA at dilution of 1:100 (40x lens).
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
If you have published an article using product 38329, please notify us so that we can cite your literature.
et al,MicroRNA-146a-5p Attenuates Fibrosis-related Molecules In Irradiated and TGF-beta1-Treated Human Hepatic Stellate Cells by RegulatIng PTPRA-SRC SignalIng. In Radiat Res on 2019 Dec by Yuan BY, Chen YH, et al..PMID:31560641
, (2019),
PMID:
31560641
The lead time is currently 2 weeks.
