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Location： Home > Polyclonal Antibodies > MMP9 antibody

MMP9 antibody#38359

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Product Detail

Product NameMMP9 antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were purified by affinity purification using immunogen.

ApplicationsWB IF

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of total MMP9 protein.

Immunogen TypePeptide

Immunogen DescA synthetic peptide of human MMP9.

Target NameMMP9

ConjugateUnconjugated

Other NamesCLG4B; GELB; MMP-9;

Accession NoSwiss-Prot#: P14780
NCBI Gene ID: 4318

Uniprot P14780

Gene ID 4318;

Sdspage MW78kd

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20˚C

Application Details

Western blotting: 1:500 - 1:2000
IF 1:50 - 1:200

Immunofluorescence analysis of rat lung using MMP9 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts from normal (control) and MMP9 knockout (KO) 293T cells, using MMP9 antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines, using MMP9 antibody at 1:1000 dilution.

The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5).

If you have published an article using product 38359, please notify us so that we can cite your literature.

et al,Long non-codIng RNA PVT1 promotes tumor progression by regulatIng the miR-143/HK2 axis In gallbladder cancer.In Mol Cancer on 2019 Mar 2 by Chen J, Yu Y, et al.. PMID: 30825877 , (2019),
PMID: 30825877
et al,A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861 , (2019),
PMID: 31594861
et al,TGF β1 mediated Smad signaling pathway and EMT in hepatic fibrosis induced by Nano NiO in vivo and in vitro.In Environ Toxicol on 2020 Apr by Zhang Q, Chang X ,et al..PMID: 31737983 , (2020),
PMID: 31737983

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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