Product Detail
Product NamePDGFRA antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total PDGFRA protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant fusion protein of human PDGFRA (NP_006197.1).
Target NamePDGFRA
ConjugateUnconjugated
Other NamesPDGFRA;CD140A;PDGFR-2;PDGFR2;GAS9;RHEPDGFRA
Accession NoUniprot:P16234
GeneID:5156
Uniprot
P16234
Gene ID
5156
Sdspage MW150-190KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunohistochemistry of paraffin-embedded mouse heart using PDGFRA Rabbit pAb.
Western blot analysis of extracts of various cell lines, using PDGFRA antibody.
Immunohistochemistry of paraffin-embedded rat spleen using PDGFRA Rabbit pAb.
Immunofluorescence analysis of U-2 OS cells using PDGFRA Rabbit pAb.
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
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et al,Single-cell RNA-Seq reveals the heterogeneity of fibroblasts within the tympanojugular paraganglioma microenvironment. In Heliyon
on 2024 Jul 31 by Shengming Wang, Boya Zhang, et al..PMID:39170307
, (2024),
PMID:
39170307