Product Detail
                                
                                                                        Product NameCX3CR1 antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                        IsotypeIgG
                                        PurificationAffinity purification
                                        ApplicationsWB,IHC,IF
                                        Species ReactivityHuman,Mouse,Rat
                                        SpecificityThe antibody detects endogenous level of total CX3CR1 protein.
                                        Immunogen TypePeptide
                                         Immunogen DescA synthetic peptide of human CX3CR1
                                         Target NameCX3CR1
                                         ConjugateUnconjugated
                                                                                 Other NamesCX3CR1;CCRL1;CMKBRL1;CMKDR1;GPR13;GPRV28;V28
                                        Accession NoUniprot:P49238
GeneID:1524
                                        Uniprot
                                        P49238
                                        
                                        Gene ID
                                        1524
                                        
                                                                                Sdspage MW52KDa
                                        Concentration1.0mg/ml
                                         FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
                                        StorageStore at -20˚C. Avoid freeze / thaw cycles.
                                                                                                                                                         
                                Application Details
                                WB	1:500 - 1:2000
IHC	1:50 - 1:200
IF	1:50 - 1:200
                             
                            
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded human colon carcinoma using CX3CR1 Rabbit pAb.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded rat spleen using CX3CR1 Rabbit pAb.
                                 
                                                                
                                    
                                    Immunofluorescence analysis of THP-1 cells using CX3CR1 Rabbit pAb.
                                 
                                                                
                                    
                                    Western blot analysis of extracts of various cell lines, using CX3CR1  antibody.
                                 
                                                             
                            
                                Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. 
                            
                            
                                If you have published an article using product 38481, please notify us so that we can cite your literature.
                                                                                                    
                                      et al,Dysregulated expression of miR-140 and miR122 compromised microglial chemotaxisand led to reduced restriction of ADpathology
 ,  (2024),
PMID:
                                     
                                 
                                                                                                                                        
                                      et al,Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology
 ,  (2024),
PMID: