Product Detail
Product NameMMP11 antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were purified by affinity purification using immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total MMP11 protein.
Immunogen TypePeptide
Immunogen DescA synthetic peptide of human MMP11.
Target NameMMP11
ConjugateUnconjugated
Other NamesST3; SL-3; STMY3
Accession NoSwiss-Prot#: P24347
NCBI Gene ID: 4320
Uniprot
P24347
Gene ID
4320;
Sdspage MW55kd
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using MMP11 at 1:500 dilution.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
If you have published an article using product 38546, please notify us so that we can cite your literature.
et al,miR-125a-3p suppresses the growth and progression of papillary thyroid carcInoma cell by targetIng MMP11. In J Cell Biochem on 2019 Sep 6. by Song M, Wang N, et al..PMID:31489990
, (2019),
PMID:
31489990
et al,miR-125a-3p suppresses the growth and progression of papillary thyroid carcinoma cell by targeting MMP11.In J Cell Biochem on 2020 Feb; by Song M, Wang N, et al..PMID:31489990
, (2020),
PMID:
31489990
The lead time is currently 2 weeks.
