Product Detail
Product NamePDK4 antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total PDK4 protein.
Immunogen TypePeptide
Immunogen DescA synthetic peptide of human PDK4
Target NamePDK4
ConjugateUnconjugated
Other NamesPDK4
Accession NoUniprot:Q16654
GeneID:5166
Uniprot
Q16654
Gene ID
5166
Sdspage MW46KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded rat heart using PDK4 Rabbit pAb.
Western blot analysis of extracts of various cell lines, using PDK4 antibody.
Immunohistochemistry of paraffin-embedded human placenta using PDK4 Rabbit pAb.
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
If you have published an article using product 38562, please notify us so that we can cite your literature.
et al,Huzhangoside A Suppresses Tumor Growth through Inhibition of Pyruvate Dehydrogenase KInase Activity. In Cancers (Basel) on 2019 May 23 by Kwak CH, Lee JH, et al..PMID: 31126094
, (2019),
PMID:
31126094
et al,Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity. In Int J Mol Sci on 2020 Aug 21 by Choong-Hwan Kwak, Ling Jin, et al..PMID:32825675
, (2020),
PMID:
32825675
The lead time is currently 2 weeks.
