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Location： Home > Polyclonal Antibodies > PRDX3 antibody

PRDX3 antibody#38567

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Product Detail

Product NamePRDX3 antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAffinity purification

ApplicationsWB,IF

Species ReactivityHuman,Mouse,Rat

SpecificityThe antibody detects endogenous level of total PRDX3 protein.

Immunogen TypePeptide

Immunogen DescRecombinant fusion protein containing a sequence of PRDX3.

Target NamePRDX3

ConjugateUnconjugated

Other NamesAOP1; MER5; AOP-1; SP-22; HBC189; PRO1748; prx-III;

Accession NoSwiss-Prot#: P30048
NCBI Gene ID: 10935

Uniprot P30048

Gene ID 10935;

Calculated MW187 kDa

Sdspage MW28kd

Concentration1.0mg/ml

FormulationPBS with 0.01% thimerosal,50% glycerol,pH7.3.

StorageStore at -20℃. Avoid freeze / thaw cycles.

Application Details

WB 1:500 - 1:2000
IF 1:50 - 1:100

Immunofluorescence analysis of NIH-3T3 cells using PRDX3 Polyclonal at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2 OS cells using PRDX3 Polyclonal at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using PRDX3 at 1:3000 dilution.

This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

If you have published an article using product 38567, please notify us so that we can cite your literature.

et al,The effect of exposure time and concentration of airborne PM2.5 on lung Injury In mice: A transcriptome analysis. In Redox Biol on 2019 Sep by Wang H, Shen X et al..PMID:31279222 , (2019),
PMID: 31279222
et al,DDAH1 Protects against Cardiotoxin-Induced Muscle Injury and Regeneration In Antioxidants (Basel)On2023 Sep 13byFei Feng , Bingqing Cui et al..PMID:37760057 , (2023),
PMID: 37760057
et al,Aerobic Exercise Protects against Cardiotoxin-Induced Skeletal Muscle Injury in a DDAH1-Dependent Manner. In Antioxidants (Basel) on 2024 Sep 1 by Fei Feng, Kai Luo, et al..PMID:39334728 , (2024),
PMID: 39334728

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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