Product Detail
Product NameMAGEB2 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsIHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total MAGEB2 protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide corresponding to residues near the N terminal of human melanoma antigen family B, 2
Target NameMAGEB2
ConjugateUnconjugated
Other NamesDAM6; CT3.2; MAGE-XP-2
Accession NoSwiss-Prot:O15479
Gene Accssion:NP_002355
Uniprot
O15479
Gene ID
4113;
Concentration2.5mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry:1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #40202 at dilution 1/40.
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using #40202 at dilution 1/40.
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.?
If you have published an article using product 40202, please notify us so that we can cite your literature.
et al,Establishment of cancer/testis antigen profiling based on clinicopathological characteristics in resected pathological stage III non-small cell lung cancer.In Cancer Manag Res.On 2018 Jul 16 by Jin S, Cao S et al..PMID: 30038519
, (2018),
PMID:
30038519
The lead time is currently 1 week.
