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TPH2 Antibody#43424

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Product Detail

Product NameTPH2 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntigen affinity purification.

ApplicationsWB IHC

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous levels of total TPH2 protein.

Immunogen DescSynthetic peptide of human TPH2

Target NameTPH2

ConjugateUnconjugated

Other NamesNTPH; ADHD7

Accession NoSwiss-Prot#: Q8IWU9
Gene ID: 121278

Uniprot Q8IWU9

Gene ID 121278;

Calculated MW56kd

Concentration1.2mg/ml

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C

Application Details
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:20-1:100
Gel: 8%SDS-PAGE
Lysate: 40 μg
Lane: Huvec cells
Primary antibody: 1/300 dilution
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 1 minute
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using #43424 at dilution 1/20.
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #43424 at dilution 1/20.

This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem.

If you have published an article using product 43424, please notify us so that we can cite your literature.

et al,Effects of Liqi Tongbian decoction on gut microbiota, SCFAs production, and 5-HT pathway in STC rats with Qi Stagnation Pattern. In Front Microbiol on 2024 Mar 15 by Qihong Liu, Danfeng Ke,et al..PMID:38559349 , (2024),
PMID: 38559349

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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