Product Detail
Product NamePIK3CA Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification
ApplicationsIHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total PIK3CA protein.
Immunogen Typepeptide
Immunogen DescSynthetic peptide of human PIK3CA
Target NamePIK3CA
ConjugateUnconjugated
Other NamesMCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
Accession NoSwiss-Prot#: P42336
NCBI Gene ID: 5290
Uniprot
P42336
Gene ID
5290;
Concentration0.7mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PIK3CA Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PIK3CA Antibody at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
If you have published an article using product 43766, please notify us so that we can cite your literature.
et al,CSF-1R regulates non-small cell lung cancer cells dissemination through Wnt3a signaling.
, (2017),
PMID:
29218239