Product Detail
                                
                                                                        Product NameCCR4 Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                                                                PurificationAntigen affinity purification
                                        ApplicationsIHC
                                        Species ReactivityHu
                                        SpecificityThe antibody detects endogenous levels of total CCR4 protein.
                                        Immunogen Typepeptide
                                         Immunogen DescSynthetic peptide of human CCR4
                                         Target NameCCR4
                                         ConjugateUnconjugated
                                                                                 Other NamesCKR4; K5-5; CD194; CMKBR4; ChemR13; CC-CKR-4; HGCN:14099
                                        Accession NoSwiss-Prot#: P51679
NCBI Gene ID: 1233
                                        Uniprot
                                        P51679
                                        
                                        Gene ID
                                        1233;
                                        
                                                                                                                        Concentration0.7mg/ml
                                         FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
                                        StorageStore at -20˚C
                                                                                                                                                         
                                Application Details
                                
Immunohistochemistry: 1: 20-100
                             
                            
                                                                
                                    
                                    The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CCR4 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
                                 
                                                                
                                    
                                    The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CCR4 Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
                                 
                                                             
                            
                                The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
                            
                            
                                If you have published an article using product 43918, please notify us so that we can cite your literature.
                                                                                                    
                                      et al,SLC35A2 expression drives breast cancer progression via ERK pathway activation
 ,  (2023),
PMID: