Product Detail
Product NameHTRA4 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification
ApplicationsWB, IHC
Species ReactivityHu, Rt
SpecificityThe antibody detects endogenous levels of total HTRA4 protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide of human HTRA4
Target NameHTRA4
ConjugateUnconjugated
Accession NoSwiss-Prot#:P83105
NCBI Gene ID:203100
Gene Accssion:NP_710159
Uniprot
P83105
Gene ID
203100;
Calculated MW51 kDa
Concentration1
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
WB dilution:1:500-2000
IHC dilution:1: 30-150
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human placenta tissue and 231 cell lysates, Primary antibody:47642(HTRA4 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47642(HTRA4 Antibody) at dilution 1/35.(Original magnification: 200)
This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
If you have published an article using product 47642, please notify us so that we can cite your literature.
et al,The epigenetic role of HTR1A antagonist in facilitating GnRH expression for pubertal initiation control
, (2021),
PMID:
34458005
et al,The epigenetic role of HTR1A antagonist in facilitating GnRH expression for pubertal initiation control
, (2021),
PMID:
34458005
Yes
