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Location： Home > Recombinant Rabbit Monoclonal Antibodies > MLKL Rabbit mAb

MLKL Rabbit mAb#48612

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Product Detail

Product NameMLKL Rabbit mAb

Clone No.SA40-04

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other Names9130019I15Rik antibody
FLJ34389 antibody
hMLKL antibody
Mixed lineage kinase domain like antibody
Mixed lineage kinase domain like protein antibody
Mixed lineage kinase domain-like protein antibody
Mlkl antibody
MLKL_HUMAN antibody

Accession NoSwiss-Prot#:Q8NB16

Uniprot Q8NB16

Gene ID 197259;

Calculated MW54 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200


Western blot analysis of MLKL on different cell lysates using anti-MLKL antibody at 1/1,000 dilution. Positive control:
Lane 1: HT29
Lane 2: HUVEC
Lane 3: Hela
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-MLKL antibody. Counter stained with hematoxylin.
MLKL (mixed lineage kinase domain-like) is a 471 amino acid protein that contains one protein kinase domain which is thought to be catalytically inactive. The gene encoding MLKL maps to chromosome 16 and is expressed as two isoforms which are produced by alternative splicing events. Chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

If you have published an article using product 48612, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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