Product Detail
Product NameJNK1+JNK2+JNK3 Rabbit mAb
Clone No.SA43-06
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, ICC/IF, IP
Species ReactivityHu, Ms, Rt, Cow, Monkey, zebrafish
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesC Jun kinase 2 antibody
c Jun N terminal kinase 1 antibody
c Jun N terminal kinase 2 antibody
c Jun N terminal kinase 3 antibody
c-Jun N-terminal kinase 1 antibody
JNK 46 antibody
JNK 55 antibody
JNK antibody
JNK-46 antibody
JNK1 antibody
JNK1A2 antibody
JNK2 antibody
JNK21B1/2 antibody
JNK2A antibody
JNK2ALPHA antibody
JNK2B antibody
JNK2BETA antibody
JNK3 alpha protein kinase antibody
JNK3 antibody
JNK3A antibody
Jun kinase antibody
JUN N terminal kinase antibody
MAP kinase 10 antibody
MAP kinase 8 antibody
MAP kinase 9 antibody
MAP kinase p49 3F12 antibody
MAPK 10 antibody
MAPK 8 antibody
MAPK 9 antibody
MAPK10 antibody
mapk8 antibody
MAPK9 antibody
Mitogen activated protein kinase 10 antibody
Mitogen activated protein kinase 8 antibody
Mitogen activated protein kinase 8 isoform JNK1 alpha1 antibody
Mitogen activated protein kinase 8 isoform JNK1 beta2 antibody
Mitogen activated protein kinase 9 antibody
Mitogen-activated protein kinase 8 antibody
MK08_HUMAN antibody
p493F12 antibody
p54a antibody
p54aSAPK antibody
p54bSAPK antibody
PRKM10 antibody
PRKM8 antibody
PRKM9 antibody
SAPK antibody
SAPK(beta) antibody
SAPK1 antibody
SAPK1a antibody
SAPK1b antibody
SAPK1c antibody
Stress activated protein kinase 1 antibody
Stress activated protein kinase 1a antibody
Stress activated protein kinase 1b antibody
Stress activated protein kinase 1c antibody
Stress activated protein kinase beta antibody
Stress activated protein kinase JNK1 antibody
Stress activated protein kinase JNK2 antibody
Stress activated protein kinase JNK3 antibody
Stress-activated protein kinase 1c antibody
Stress-activated protein kinase JNK1 antibody
Accession NoSwiss-Prot#:P45983
Uniprot
P45983
Gene ID
5599;
Calculated MW46/54 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-5,000
ICC: 1:50-1:200
Western blot analysis of JNK1+JNK2+JNK3 on different cell lysates using anti-JNK1+JNK2+JNK3 antibody at 1/1,000 dilution. Positive control:
Lane 1: Hela
Lane 2: PC12
Lane 3: K562
Lane 5: HepG2
Lane 6: Human lung
Western blot analysis of JNK1+JNK2+JNK3 on hybrid fish (crucian-carp) brain tissue lysate using anti-JNK1+JNK2+JNK3 antibody at 1/500 dilution.
ICC staining JNK1+JNK2+JNK3 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2, and JNK3b2, which represent the p54 isoforms.JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun, and other signaling kinases, including MEKK1 and p38.
If you have published an article using product 48615, please notify us so that we can cite your literature.
et al,5鈥慛itro锟?锟?3鈥憄henylpropylamino) benzoic acid induces apoptosis of human lens epithelial cells via reactive oxygen species and endoplasmic reticulum stress through the mitochondrial apoptosis pathway. In Int J Mol Med on 2021 Apr by Lingzhi Niu, Xin Liu,et al..PMID:33604681
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PMID:
33604681
et al,Gingerenone A Attenuates Ulcerative Colitis via Targeting IL-17RA to Inhibit Inflammation and Restore Intestinal Barrier Function. In Adv Sci (Weinh) on 2024 Jul by Jian Liang, Weigang Dai,et al..PMID:38639442
, (2024),
PMID:
38639442
et al,Novel oxicam nonsteroidal compound XK01 attenuates inflammation by suppressing the NF-κB and MAPK pathway in RAW264.7 macrophages. In Heliyon on 2024 Jan 9 by Jixiang Wang, Jiawang Tan,et al..PMID:38312593
, (2024),
PMID:
38312593
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