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PSD95 Rabbit mAb#48638

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Product Detail

Product NamePSD95 Rabbit mAb

Clone No.SR38-09

ClonalityMonoclonal

PurificationAffinity-chromatography

ApplicationsWB, ICC/IF, IHC, IP, FC

Species ReactivityHu, Ms, Rt

Immunogen DescA synthesized peptide derived from human Disks large homolog 4

ConjugateUnconjugated

Other NamesDiscs large homolog 4 antibody
Disks large homolog 4 antibody
DLG 4 antibody
Dlg4 antibody
DLG4_HUMAN antibody
FLJ97752 antibody
FLJ98574 antibody
Human post synaptic density protein 95 antibody
Post synaptic density protein 95 antibody
Postsynaptic density protein 95 antibody
PSD 95 antibody
PSD-95 antibody
PSD95 antibody
SAP 90 antibody
SAP-90 antibody
SAP90 antibody
Synapse associated protein 90 antibody
Synapse-associated protein 90 antibody
Tax interaction protein 15 antibody

Accession NoSwiss-Prot#:P78352

Uniprot P78352

Gene ID 1742;

Calculated MW100 kDa

FormulationRabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

StorageStore at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Application Details

WB 1:1000-1:2000
IHC 1:100-1:200
ICC/IF 1:50-1:200
IP 1:20-1:50
FC 1:20-1:100

Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-PSD95 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded rat cerebellum tissue using anti-PSD95 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse cerebullum tissue using anti-PSD95 antibody. Counter stained with hematoxylin.

Flow cytometric analysis of SH-SY-5Y cells with PSD95 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Western blot analysis of PSD95 expression in Mouse brain tissue lysate.
Immunofluorescent analysis of U87-MG cells, using PSD95 Antibody.

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons.

If you have published an article using product 48638, please notify us so that we can cite your literature.

et al,Qingzhuan dark tea Theabrownin alleviates hippocampal injury in HFD-induced obese mice through the MARK4/NLRP3 pathway , (2024),
PMID:

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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