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Location： Home > Recombinant Rabbit Monoclonal Antibodies > PI 3 Kinase p55 gamma Rabbit mAb

PI 3 Kinase p55 gamma Rabbit mAb#48645

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Product NamePI 3 Kinase p55 gamma Rabbit mAb

Clone No.SR44-06

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesDKFZp686P05226 antibody
FLJ41892 antibody
OTTHUMP00000009783 antibody
OTTHUMP00000009786 antibody
p55 antibody
p55 gamma antibody
P55G_HUMAN antibody
p55PIK antibody
Phosphatidylinositol 3 kinase regulatory subunit gamma antibody
Phosphatidylinositol 3 kinase regulatory subunit polypeptide 3 antibody
Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55, gamma) antibody
Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma antibody
Phosphatidylinositol 3-kinase regulatory subunit gamma antibody
Phosphoinositide 3 kinase regulatory subunit 3 (gamma) antibody
Phosphoinositide 3 kinase regulatory subunit 3 antibody
Phosphoinositide 3 kinase regulatory subunit polypeptide 3 antibody
Phosphoinositide 3 kinase, regulatory subunit 3 (p55, gamma) antibody
Phosphoinositide 3 kinase, regulatory subunit, polypeptide 3 (p55, gamma) antibody
PI3 kinase p85 subunit gamma antibody
PI3-kinase regulatory subunit gamma antibody
PI3-kinase subunit p55-gamma antibody
PI3K regulatory subunit gamma antibody
Pik3r3 antibody
PtdIns 3 kinase p85 gamma antibody
PtdIns-3-kinase regulatory subunit gamma antibody
PtdIns-3-kinase regulatory subunit p55-gamma antibody

Accession NoSwiss-Prot#:Q92569

Uniprot Q92569

Gene ID 8503;

Calculated MW54 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:10,000
IHC: 1:200-1:500
ICC: 1:50-1:200

Western blot analysis of PI 3 Kinase p55 γ on different lysates using anti-PI 3 Kinase p55 γ antibody at 1/1,000 dilution. Positive control:
Lane 1: MCF-7
Lane 2: Jurkat
Lane 3: Mouse testis
Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-PI 3 Kinase p55 �� antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PI 3 Kinase p55 �� antibody. Counter stained with hematoxylin.
ICC staining PI 3 Kinase p55 γ in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining PI 3 Kinase p55 γ in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3 position. PI 3-kinase p55γ (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55γ protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55γ mRNAs are expressed in most human fetal and adult tissues; predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55γ have been identified; one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55γ interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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