Product Detail
Product Name5T4 Rabbit mAb
Clone No.SU34-05
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IP
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Names5T4 antibody 5T4 oncofetal antigen antibody 5T4 oncofetal trophoblast glycoprotein antibody 5T4 oncotrophoblast glycoprotein antibody 5T4AG antibody AW495680 antibody M6P1 antibody TPBG antibody TPBG_HUMAN antibody Trophoblast glycoprotein antibody
Accession NoSwiss-Prot#:Q13641
Uniprot
Q13641
Gene ID
7162;
Calculated MW72 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-5,000
Western blot analysis of 5T4 on MCF-7 cells lysates using anti-5T4 antibody at 1/1,000 dilution.
TPBG (trophoblast glycoprotein), also known as 5T4, M6P1 or 5T4AG, is a 420 amino acid single-pass type I membrane protein expressed by all types of trophoblasts as early as 9 weeks of development. TPBG contains an N-terminal putative signal sequence, a 310-residue extracellular region, a membrane anchorage domain and a 44-amino acid cytoplasmic tail with a potential phosphorylation site. The extracellular region has seven potential N-glycosylation sites and seven leucine-rich repeats, which are located in two regions separated by a hydrophilic stretch. Suggested to be involved in cell adhesion, TPBG may also be associated with tumor growth and progression.
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