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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Aurora A Rabbit mAb

Aurora A Rabbit mAb#48861

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Product Detail

Product NameAurora A Rabbit mAb

Clone No.ST46-07

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, FC

Species ReactivityHu, Ms

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesAIK antibody
ARK-1 antibody
ARK1 antibody
AURA antibody
Aurka antibody
Aurora 2 antibody
Aurora A antibody
Aurora kinase A antibody
Aurora-related kinase 1 antibody
Aurora/IPL1 like kinase antibody
Aurora/IPL1-related kinase 1 antibody
AURORA2 antibody
Breast tumor-amplified kinase antibody
BTAK antibody
hARK1 antibody
IAK antibody
IPL1 related kinase antibody
MGC34538 antibody
OTTHUMP00000031340 antibody
OTTHUMP00000031341 antibody
OTTHUMP00000031342 antibody
OTTHUMP00000031343 antibody
OTTHUMP00000031344 antibody
OTTHUMP00000031345 antibody
OTTHUMP00000166071 antibody
OTTHUMP00000166072 antibody
PPP1R47 antibody
Protein phosphatase 1, regulatory subunit 47 antibody
Serine/threonine kinase 15 antibody
Serine/threonine kinase 6 antibody
Serine/threonine-protein kinase 15 antibody
Serine/threonine-protein kinase 6 antibody
Serine/threonine-protein kinase aurora-A antibody
STK15 antibody
STK6 antibody
STK6_HUMAN antibody
STK7 antibody

Accession NoSwiss-Prot#:O14965

Uniprot O14965

Gene ID 6790;

Calculated MW46 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:2,000

ICC: 1:100-1:500

FC: 1:50-1:100
ICC staining Aurora A in SKOV-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining Aurora A in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining Aurora A in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of Hela cells with Aurora A antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as secondary antibody
Activation of the oncogenic protein kinase Aurora A regulates meiotic and mitotic cell cycles in eukaryotic cells. Specifically, Aurora A plays a key role in G2/M progression. Activation occurs via autophosphorylation, and while 14 sites are subject to this, only the threonine residue at position 295 is required for activity. Though autophosphorylation mediates activation, a number of other proteins influence activation, including the spindle assembly factor TPX2 and p53

If you have published an article using product 48861, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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