Product Detail
Product NameDGCR8 Rabbit mAb
Clone No.ST04-79
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, ICC/IF, IP
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesDGCRK6 antibody C22orf12 antibody D16H22S788E antibody D16Wis2 antibody DGCR 8 antibody Dgcr8 antibody DGCR8 microprocessor complex subunit antibody DGCR8_HUMAN antibody DGCRK 6 antibody DiGeorge syndrome critical region 8 antibody DiGeorge syndrome critical region gene 8 antibody Gy1 antibody Microprocessor complex subunit DGCR8 antibody pasha antibody
Accession NoSwiss-Prot#:Q8WYQ5
Uniprot
Q8WYQ5
Gene ID
54487;
Calculated MW100 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-1:2,000
ICC: 1:50-1:200
Western blot analysis of DGCR8 on different lysates using anti-DGCR8 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: PC12 Lane 3: NIH/3T3
ICC staining DGCR8 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining DGCR8 in PC12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
DGS8, also designated DiGeorge syndrome critical region 8 protein, plays a role in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS). It is a ubiquitously expressed protein encoded by the gene DGCR8, which is deleted in DiGeorge syndrome. DiGeorge syndrome is characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. In mouse, DGS8 is detected primarily in embryonic brain, vessels, thymus and palate.
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