Product Detail
                                
                                                                        Product NameLysozyme Rabbit mAb
                                        Clone No.ST50-02
                                         Host SpeciesRecombinant Rabbit
                                         Clonality Monoclonal
                                                                                PurificationProA affinity purified
                                        ApplicationsWB, ICC/IF, IHC, IP
                                        Species ReactivityHu, Ms
                                                                                                                         Immunogen Descrecombinant protein
                                                                                 ConjugateUnconjugated
                                                                                 Other Names1 4 beta N acetylmuramidase C antibody 1 antibody 4-beta-N-acetylmuramidase C antibody EC 3.2.1.17 antibody LYSC_HUMAN antibody Lysosyme antibody Lysozyme (renal amyloidosis) antibody Lysozyme C antibody Lysozyme C precursor antibody LYZ antibody LZM antibody Renal amyloidosis antibody
                                        Accession NoSwiss-Prot#:P61626
                                        Uniprot
                                        P61626
                                        
                                        Gene ID
                                        4069;
                                        
                                        Calculated MW17 kDa
                                                                                                                         Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
                                        StorageStore at -20˚C
                                                                                                                                                         
                                Application Details
                                WB: 1:1,000-1:2,000 
IHC: 1:200-1:500
ICC: 1:50-1:200
                             
                            
                                                                
                                    
                                    Western blot analysis of Lysozyme on different lysates using anti-Lysozyme antibody at 1/1,000 dilution. Positive control:   Lane 1: Mouse kidney      Lane 2: HL-60
                                 
                                                                
                                    
                                    Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Lysozyme antibody. Counter stained with hematoxylin.
                                 
                                                                
                                    
                                    Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Lysozyme antibody. Counter stained with hematoxylin. The nuclear counter stain is DAPI (blue).
                                 
                                                                
                                    
                                    Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Lysozyme antibody. Counter stained with hematoxylin.
                                 
                                                                
                                    
                                    Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-Lysozyme antibody. Counter stained with hematoxylin.
                                 
                                                                
                                    
                                    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Lysozyme antibody. Counter stained with hematoxylin.
                                 
                                                                
                                    
                                    ICC staining Lysozyme in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
                                 
                                                             
                            
                                The origins of the lysozyme proteins date back an estimated 400 to 600 million years. Generally, lysozyme genes are relatively small, roughly 10 kilobases in length, and composed of four exons and three introns. Originally a bacteriolytic defensive agent, the function of this family of proteins adapted to serve a digestive function in its present forms. Lysozymes in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lysozyme C belongs to the glycosyl hydrolase 22 family, and newly identified relatives of Lysozyme C appear to possess anti-HIV activity, as well as preserved bacteriolytic function against Micrococcus lysodeikticus. Lysozyme C is capable of both hydrolysis and transglycosylation and also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides. Lysozyme C defects are a cause of amyloidosis VIII, also called familial visceral or Ostertag-type amyloidosis.
                            
                            
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