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Location： Home > Recombinant Rabbit Monoclonal Antibodies > SOX10 Rabbit mAb

SOX10 Rabbit mAb#49105

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Product Detail

Product NameSOX10 Rabbit mAb

Clone No.SN20-41

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesDOM antibody
DOM antibody
Dominant megacolon mouse human homolog of antibody
MGC15649 antibody
PCWH antibody
SOX 10 antibody
SOX10 antibody
SOX10_HUMAN antibody
SRY (sex determining region Y) box 10 antibody
SRY (sex determining region Y) box 10 antibody
SRY box 10 antibody
SRY box containing gene 10 antibody
SRY related HMG box gene 10 antibody
SRY related HMG box gene 10 antibody
Transcription factor SOX 10 antibody
Transcription factor SOX-10 antibody
WS2E antibody
WS4 antibody
WS4C antibody

Accession NoSwiss-Prot#:P56693

Uniprot P56693

Gene ID 6663;

Calculated MW60 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:2,000

ICC: 1:100-1:500

Western blot analysis of SOX10 on different lysates using anti-SOX10 antibody at 1/1,000 dilution. Positive control:
Lane 1: Mouse brain
Lane 2: HepG2
ICC staining SOX10 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining SOX10 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining SOX10 in RH-35 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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