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Delta Opioid Receptor Rabbit mAb#49109

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Product Detail

Product NameDelta Opioid Receptor Rabbit mAb

Clone No.SN20-04

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesD-OR-1 antibody
Delta type opioid receptor antibody
Delta type opioid receptor DOR 1 antibody
Delta type opioid receptor DOR1 antibody
Delta-type opioid receptor antibody
DOR 1 antibody
DOR-1 antibody
DOR1 antibody
mDOR antibody
Nbor antibody
Opioid receptor delta 1 antibody
OPRD 1 antibody
OPRD antibody
OPRD_HUMAN antibody
Oprd1 antibody

Accession NoSwiss-Prot#:P41143

Uniprot P41143

Gene ID 4985;

Calculated MW40 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000



FC: 1:50-1:100
Western blot analysis of OPRD1 on different lysates using anti-OPRD1 antibody at 1/1,000 dilution. Positive control:
Lane 1: HUVEC
Lane 2: Rat brain
Flow cytometric analysis of SH-SY-5Y cells with OPRD1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
Endogenous opioid peptides and opiates, like morphine, transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor, mu-type, delta-type and kappa-type, also designated MOR-1, DOR-1 and KOR-1, respectively. MOR-1 is a receptor for beta-endorphin, DOR-1 is a receptor for enkephalins, and KOR-1 is a receptor for dynorphins. The three opioid receptor types are highly homologous and belong to the superfamily of G protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions, including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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