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TWEAKR Rabbit mAb#49110

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Product Detail

Product NameTWEAKR Rabbit mAb

Clone No.SN20-07

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, IP

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesCD 266 antibody
CD266 antibody
CD266 antigen antibody
FGF inducible 14 antibody
FGF-inducible 14 antibody
Fibroblast growth factor inducible immediate early response protein 14 antibody
Fibroblast growth factor-inducible immediate-early response protein 14 antibody
FN 14 antibody
FN14 antibody
TNFRSF 12A antibody
TNFRSF12A antibody
TNR12_HUMAN antibody
Tumor necrosis factor receptor superfamily member 12A antibody
TWEAK R antibody
Tweak receptor antibody
Tweak-receptor antibody
TweakR antibody

Accession NoSwiss-Prot#:Q9NP84

Uniprot Q9NP84

Gene ID 51330;

Calculated MW14 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB: 1:500-1:1000
IHC: 1:50-1:200
 

Western blot analysis of TWEAKR on different lysates using anti-TWEAKR antibody at 1/1,000 dilution. Positive control:
Lane 1: NIH/3T3
Lane 2: C2C12
Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.

Fn14, the TWEAK receptor, is a recently identified member of the TNF receptor superfamily and is expressed on smooth muscle cells and endothelial cells. It is a weak inducer of apoptosis and promotes angiogenesis. Fn14 is a type 1 membrane protein. It associates with TRAF1 and TRAF2, and may modulate cellular adhesion to matrix proteins. Fn14 is highly expressed in heart, placenta and kidney, and moderately expressed in lung, skeletal muscle and pancreas. It is the smallest member of the TNF receptor (TNFR) superfamily described to date, and signals via recruitment of several different TNFR-associated factors.

If you have published an article using product 49110, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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