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Location： Home > Recombinant Rabbit Monoclonal Antibodies > RON Rabbit mAb

RON Rabbit mAb#49195

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Product Detail

Product NameRON Rabbit mAb

Clone No.SD2006

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, IP, FC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other Namesc met related tyrosine kinase antibody
CD136 antibody
CD136 antigen antibody
CDw136 antibody
Macrophage stimulating 1 receptor (c met related tyrosine kinase) antibody
Macrophage stimulating 1 receptor antibody
Macrophage stimulating protein receptor alpha chain antibody
MACROPHAGE STIMULATING PROTEIN RECEPTOR antibody
Macrophage stimulating protein receptor beta chain antibody
Macrophage-Stimulating 1 Receptor (MST1R) antibody
Macrophage-stimulating protein receptor beta chain antibody
MSP receptor antibody
Mst1r antibody
MST1R variant RON30 antibody
MST1R variant RON62 antibody
NPCA3 antibody
p185 RON antibody
p185-Ron antibody
Protein-tyrosine kinase 8 antibody
PTK 8 antibody
ptk8 antibody
PTK8 protein tyrosine kinase 8 antibody
Recepteur dorigine nantais (RON) antibody
RON antibody
RON protein tyrosine kinase antibody
RON variant E2E3 antibody
RON_HUMAN antibody
Soluble RON variant 1 antibody
Soluble RON variant 2 antibody
Soluble RON variant 3 antibody
Soluble RON variant 4 antibody
Stem cell derived tyrosine kinase antibody

Accession NoSwiss-Prot#:Q04912

Uniprot Q04912

Gene ID 4486;

Calculated MW185 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC: 1:50-1:100
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-RON antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-RON antibody. Counter stained with hematoxylin.
ICC staining RON in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining RON in AGS cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining RON in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of THP-1 cells with RON antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
Receptor protein tyrosine kinases (PTKs) have been classified into different subclasses on the basis of sequence similarity and distinct structural characteristics. The c-Met encoded receptor represents the initial member of one class of receptors characterized by a heterodimeric structure and a cysteine-rich extracellular domain. Ron, also designated macrophage-stimulating protein receptor (MSP receptor), p185-Ron, CD136 antigen or PTK8 represents a second member of this receptor class. The intracellular PTK domains of Ron and Met are highly similar (63% sequence identity) while the extracellular domains are less related (25% sequence identity) and both are rich in cysteine residues. Mature Ron receptor is comprised of a disulfide-linked heterodimer formed from an alpha chain (Ron α) and a beta chain (Ron β). Proteolytic processing results in the separation of the N-terminal Ron α and C-terminal Ron β subunits.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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