Welcome to Sabbiotech!     
Email:info@signalwayantibody.com
Welcome Login Register My Cart(0,$0.00)
Location： Home > Recombinant Rabbit Monoclonal Antibodies > Cdc37 Rabbit mAb

Cdc37 Rabbit mAb#49221

Datasheet PDF
Availability： Yes
Total Amount:$
ADD TO CART
Detail Pictures Description Publish(0) Other
Product Detail

Product NameCdc37 Rabbit mAb

Clone No.JJ087-06

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, IP, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesCDC 37 antibody
Cdc37 antibody
CDC37 cell division cycle 37 homolog antibody
CDC37 cell division cycle 37 S cerevisiae homolog antibody
CDC37 cell division cycle 37, S cerevisiae, homolog of antibody
Cdc37 homolog antibody
CDC37 protein antibody
CDC37_HUMAN antibody
CDC37A antibody
cell division cycle 37 antibody
Cell division cycle 37 homolog antibody
Hsp90 chaperone protein kinase targeting subunit antibody
Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody
Hsp90 chaperone protein kinase-targeting subunit antibody
Hsp90 co chaperone Cdc37 antibody
Hsp90 co-chaperone Cdc37 antibody
p50 antibody
p50Cdc37 antibody
S cerevisiae hypothetical protein CDC37 antibody

Accession NoSwiss-Prot#:Q16543

Uniprot Q16543

Gene ID 11140;

Calculated MW45 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200


FC: 1:50-1:100
Western blot analysis of Cdc37 on different lysates using anti-Cdc37 antibody at 1/1,000 dilution. Positive control:
Lane 1: Jurkat
Lane 2: A431
Lane 3: K562
Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Cdc37 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-Cdc37 antibody. Counter stained with hematoxylin.
Flow cytometric analysis of Hela cells with Cdc37 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with Hsp90. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.

If you have published an article using product 49221, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

QUICK NAV

New Products

Cell Signal Transduction

Cancer

Stem Cell

Neuroscience

Help and Support

Contact Us

Terms

Privacy Policy

support

Distributors