Product Detail
Product NameVE Cadherin Rabbit mAb
Clone No.JJ0941
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB,IP
Species ReactivityMs
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Names7B 4 antibody 7B4 antibody 7B4 antigen antibody CADH5_HUMAN antibody Cadherin 5 antibody Cadherin 5 type 2 antibody Cadherin 5, type 2 (vascular endothelium) antibody Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody cadherin, vascular endothelial antibody cadherin, vascular endothelial, 1 antibody Cadherin-5 antibody Cadherin5 antibody CD 144 antibody CD144 antibody CD144 antigen antibody CDH 5 antibody CDH5 antibody CDH5 protein antibody Endothelial specific cadherin antibody FLJ17376 antibody OTTHUMP00000174777 antibody Vascular endothelial cadherin antibody Vascular epithelium cadherin antibody VE Cad antibody VE-cadherin antibody VEC antibody
Accession NoSwiss-Prot#:P55284
Uniprot
P55284
Gene ID
12562;
Calculated MW88/125 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-5,000
Western blot analysis of VE Cadherin on different lysates using anti-VE Cadherin antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse heart Lane 2: Mouse placenta Lane 3: Mouse spleen Lane 4: Mouse lung
The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.
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