Welcome to Sabbiotech!     
Email:info@signalwayantibody.com
Welcome Login Register My Cart(0,$0.00)
Location： Home > Recombinant Rabbit Monoclonal Antibodies > Doublecortin Rabbit mAb

Doublecortin Rabbit mAb#49313

Datasheet PDF
Availability： Yes
Total Amount:$
ADD TO CART
Detail Pictures Description Publish(0) Other
Product Detail

Product NameDoublecortin Rabbit mAb

Clone No.JJ0959

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, FC

Species ReactivityHu, Ms, Rt

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesDBCN antibody
Dbct antibody
DC antibody
DCX antibody
DCX_HUMAN antibody
Doublecortex antibody
Doublin antibody
FLJ51296 antibody
Lis X antibody
Lis-X antibody
Lissencephalin X antibody
Lissencephalin-X antibody
Lissencephaly X linked antibody
Lissencephaly X linked doublecortin antibody
LISX antibody
Neuronal migration protein doublecortin antibody
OTTHUMP00000023859 antibody
OTTHUMP00000023860 antibody
OTTHUMP00000216315 antibody
OTTHUMP00000216316 antibody
SCLH antibody
XLIS antibody

Accession NoSwiss-Prot#:O43602

Uniprot O43602

Gene ID 1641;

Calculated MW41 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000



FC: 1:50-1:100
Western blot analysis of Doublecortin on human brain lysates using anti-Doublecortin antibody at 1/1,000 dilution.
Flow cytometric analysis of HepG2 cells with Doublecortin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface, resulting in severe mental retardation. Genetic analysis identified two proteins that are mutated in some cases of lissencephaly, designated lissencephaly-1 protein (LIS1) and doublecortin. LIS1 shows sequence homology to β-subunits of heterotrimeric G proteins. Doublecortin contains a consensus Abl phosphorylation site, and it has some sequence homology to a predicted kinase protein. Both proteins are highly expressed in developing brain, suggesting that they may be involved in a signal transduction pathway that is crucial to brain development.

If you have published an article using product 49313, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

QUICK NAV

New Products

Cell Signal Transduction

Cancer

Stem Cell

Neuroscience

Help and Support

Contact Us

Terms

Privacy Policy

support

Distributors