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S100A10 Rabbit mAb#49352

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Product Detail

Product NameS100A10 Rabbit mAb

Clone No.JF0987

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC

Species ReactivityHu, Ms

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other Names42C antibody
AA409961 antibody
AL024248 antibody
Annexin II ligand antibody
Annexin II ligand, calpactin I, light polypeptide antibody
Annexin II tetramer (AIIt) p11 subunit antibody
Annexin II, light chain antibody
ANX2L antibody
ANX2LG antibody
Ca[1] antibody
CAL12 antibody
CAL1L antibody
Calpactin I light chain antibody
Calpactin I, p11 subunit antibody
Calpactin-1 light chain antibody
Cellular ligand of annexin II antibody
CLP11 antibody
GP11 antibody
MGC111133 antibody
Nerve growth factor-induced protein 42C antibody
OTTHUMP00000015269 antibody
OTTHUMP00000015270 antibody
p10 antibody
p10 protein antibody
p11 antibody
Protein S100 A10 antibody
Protein S100-A10 antibody
S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) antibody
S100 calcium binding protein A10 (calpactin) antibody
S100 calcium binding protein A10 antibody
S100 calcium-binding protein A10 antibody
S100a10 antibody
S10AA_HUMAN antibody

Accession NoSwiss-Prot#:P60903

Uniprot P60903

Gene ID 6281;

Calculated MW11 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200


Western blot analysis of S100A10 on human lung lysates using anti-S100A10 antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human gastric carcinoma tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-S100A10 antibody. Counter stained with hematoxylin.
The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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