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Location： Home > Recombinant Rabbit Monoclonal Antibodies > ABCG2 Rabbit mAb

ABCG2 Rabbit mAb#49354

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Product Detail

Product NameABCG2 Rabbit mAb

Clone No.SR4537

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, ICC/IF, IHC, FC

Species ReactivityHu, Ms

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesABC transporter antibody
ABC15 antibody
ABCG 2 antibody
ABCG2 antibody
ABCG2_HUMAN antibody
ABCP antibody
ATP binding cassette sub family G (WHITE) member 2 antibody
ATP binding cassette transporter G2 antibody
ATP-binding cassette sub-family G member 2 antibody
BCRP antibody
BCRP1 antibody
BMDP antibody
Breast cancer resistance protein antibody
CD338 antibody
CDw338 antibody
CDw338 antigen antibody
EST157481 antibody
GOUT1 antibody
MGC102821 antibody
Mitoxantrone resistance associated protein antibody
Mitoxantrone resistance-associated protein antibody
MRX antibody
Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 antibody
MXR antibody
MXR1 antibody
Placenta specific ATP binding cassette transporter antibody
Placenta specific MDR protein antibody
Placenta-specific ATP-binding cassette transporter antibody
UAQTL1 antibody

Accession NoSwiss-Prot#:Q9UNQ0

Uniprot Q9UNQ0

Gene ID 9429;

Calculated MW72 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC: 1:50-1:100
Western blot analysis of ABCG2 on different lysates using anti-ABCG2 antibody at 1/1,000 dilution. Positive control:
Lane 1: HepG2
Lane 2: Human placenta
Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-ABCG2 antibody. Counter stained with hematoxylin.
ICC staining ABCG2 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining ABCG2 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining ABCG2 in 293T cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of 293T cells with ABCG2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extracellular and intracellular membranes through the energy of ATP hydrolysis. The ABC half-transporter, ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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