Product Detail
Product NamePrealbumin Rabbit mAb
Clone No.JF1016
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC, IP
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesAmyloid polyneuropathy antibody Amyloidosis I antibody ATTR antibody Carpal tunnel syndrome 1 antibody CTS antibody CTS1 antibody Dysprealbuminemic euthyroidal hyperthyroxinemia antibody Dystransthyretinemic hyperthyroxinemia antibody Epididymis luminal protein 111 antibody HEL111 antibody HsT2651 antibody PALB antibody Prealbumin amyloidosis type I antibody Prealbumin antibody Prealbumin Thyroxine-binding antibody Senile systemic amyloidosis antibody TBPA antibody Thyroxine binding prealbumin antibody Transthyretin antibody TTHY_HUMAN antibody TTR antibody TTR protein antibody
Accession NoSwiss-Prot#:P02766
Uniprot
P02766
Gene ID
7276;
Calculated MW16 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-1:2,000
IHC: 1:50-1:200
Western blot analysis of Prealbumin on human lung lysates using anti-Prealbumin antibody at 1/1,000 dilution.
Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Prealbumin antibody. Counter stained with hematoxylin.
Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein). The gene encoding Prealbumin maps to human chromosome 18q12.1.
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