Product Detail
Product NameCD41 Rabbit mAb
Clone No.JM11-19
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Namesantigen CD41 antibody
BDPLT16 antibody
BDPLT2 antibody
CD41 antibody
CD41B antibody
form 2 antibody
GP2B antibody
GPalpha IIb antibody
GPIIb antibody
GT antibody
GTA antibody
HPA3 antibody
Integrin alpha 2b antibody
Integrin alpha IIb antibody
Integrin alpha-IIb light chain antibody
Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody
ITA2B_HUMAN antibody
Itga2b antibody
ITGAB antibody
platelet fibrinogen receptor, alpha subunit antibody
platelet glycoprotein IIb of IIb/IIIa complex antibody
Platelet membrane glycoprotein IIb antibody
platelet specific antigen BAK antibody
PPP1R93 antibody
Accession NoSwiss-Prot#:P08514
Uniprot
P08514
Gene ID
3674;
Calculated MW113 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200
Western blot analysis of CD41 on human placenta cells lysates using anti-CD41 antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD41 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD41 antibody. Counter stained with hematoxylin.
Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
If you have published an article using product 49450, please notify us so that we can cite your literature.
Yes
