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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Growth Hormone Rabbit mAb

Growth Hormone Rabbit mAb#49460

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Product Detail

Product NameGrowth Hormone Rabbit mAb

Clone No.JM108-09

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IP, IHC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesgH antibody
GH-N antibody
GH1 antibody
GHB5 antibody
GHN antibody
Growth hormone 1 antibody
Growth hormone antibody
Growth hormone B5 antibody
Growth hormone, normal antibody
Growth hormone, pituitary antibody
HG1 antibody
hGH-N antibody
IGHD1B antibody
Pituitary growth hormone antibody
RNGHGP antibody
SOMA_HUMAN antibody
Somatotropin antibody

Accession NoSwiss-Prot#:P01241

Uniprot P01241

Gene ID 2688;

Calculated MW25 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200


Western blot analysis of Growth Hormone on human placenta cells lysates using anti- Growth Hormone antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Growth Hormone antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Growth Hormone antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-Growth Hormone antibody. Counter stained with hematoxylin.
Pituitary growth hormone (GH), also designated somatotropin, plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is secreted in a pulsatile pattern which is tightly controlled by the interplay of GH-releasing hormone (GHRH) and somatostatin (SRIF). GHRH and SRIF are the primary hypothalamic factors that determine GH secretion from the somatotroph and regulate GH synthesis and secretory reserve. GH output is also highly sensitive to feedback control by GH itself, as well as by insulin-like growth factor I. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Human growth hormone contains 191 amino acid residues with two disulfide bridges.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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