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L1CAM Rabbit mAb#49464

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Product Detail

Product NameL1CAM Rabbit mAb

Clone No.JM11-05

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IHC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesAntigen identified by monoclonal antibody
R1 antibody
CAML1 antibody
CD171 antibody
CD171 antigen antibody
HSAS antibody
HSAS1 antibody
Hyd antibody
L1 antibody
L1 cell adhesion molecule antibody
L1-NCAM antibody
L1cam antibody
L1CAM_HUMAN antibody
MASA antibody
MIC5 antibody
N CAML1 antibody
N-CAM-L1 antibody
NCAM-L1 antibody
NCAML1 antibody
Nerve-growth factor-inducible large external glycoprotein antibody
Neural cell adhesion molecule L1 antibody
NILE antibody
OTTHUMP00000025992 antibody
S10 antibody
SPG1 antibody

Accession NoSwiss-Prot#:P32004

Uniprot P32004

Gene ID 3897;

Calculated MW85/250 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:1,000-5,000
IHC: 1:50-1:200


Western blot analysis of L1CAM on different cells lysates using anti-L1CAM antibody at 1/500 dilution. Positive control��
Line 1: Hela
Line 2: human brain
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-L1CAM antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human thyroid tissue using anti-L1CAM antibody. Counter stained with hematoxylin.
Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors, including neuroblastomas, rhabdomyosarcomas, Wilm's tumors, Ewing's sarcomas and some primitive myeloid malignancies. The NCAM-L1 adhesion molecule (CD171) plays an important role in axon guidance and cell migration in the nervous system. The presence of NCAM-L1 might contribute to tumor progression by promoting cell adhesion and migration and is known to be expressed by neurons, neuroblastomas and other malignant tumors.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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