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Location： Home > Recombinant Rabbit Monoclonal Antibodies > TIMP2 Rabbit mAb

TIMP2 Rabbit mAb#49494

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Product Detail

Product NameTIMP2 Rabbit mAb

Clone No.JM87-10

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, FC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesCSC 21K antibody
CSC-21K antibody
CSC21K antibody
Metalloproteinase inhibitor 2 antibody
Metalloproteinase inhibitor 2 precursor antibody
TIMP 2 antibody
TIMP metallopeptidase inhibitor 2 antibody
TIMP-2 antibody
TIMP2 antibody
TIMP2_HUMAN antibody
Tissue Inhibitor of Metalloproteinase 2 antibody
Tissue inhibitor of metalloproteinases 2 antibody

Accession NoSwiss-Prot#:P16035

Uniprot P16035

Gene ID 7077;

Calculated MW22 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000



FC: 1:10-1:50
Western blot analysis of TIMP2 on K562 cells lysates using anti-TIMP2 antibody at 1/500 dilution.
Flow cytometric analysis of Hela cells with TIMP2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases 1, 2, 3 and 4) complex with metalloproteinases such as collagenases, gelatin-ases and stromelysins, resulting in irreversible inactivation of the metallopro-teinase. TIMP-1 has been found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus and remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart, with low levels expressed in liver, brain, lung, thymus and spleen.

If you have published an article using product 49494, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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