Product Detail
Product NamemGluR1 Rabbit mAb
Clone No.JM11-61
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC
Species ReactivityHu, Ms, Rt
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesGlutamate receptor metabotropic 1 antibody
glutamate receptor, metabotropic 1 antibody
GPRC1A antibody
GRM1 antibody
GRM1-Alpha antibody
GRM1_HUMAN antibody
GRM1A antibody
Metabotropic glutamate receptor 1 antibody
mGlu1 antibody
mGluR1 antibody
MGLUR1-Alpha antibody
MGLUR1A antibody
SCAR13 antibody
Accession NoSwiss-Prot#:Q13255
Uniprot
Q13255
Gene ID
2911;
Calculated MW200 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
IHC: 1:50-1:200
Western blot analysis of mGluR1 on rat brain cells lysates using anti-mGluR1 antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-mGluR1 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-mGluR1 antibody. Counter stained with hematoxylin.
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
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