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delta Sarcoglycan Rabbit mAb#49501

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Product Detail

Product Namedelta Sarcoglycan Rabbit mAb

Clone No.JM61-10

Host SpeciesRecombinant Rabbit

Clonality Monoclonal

PurificationProA affinity purified

ApplicationsWB, IP, IHC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other Names35 kDa dystrophin associated glycoprotein antibody
35 kDa dystrophin-associated glycoprotein antibody
35DAG antibody
CMD1L antibody
DAGD antibody
Delta-sarcoglycan antibody
Delta-SG antibody
Dystrophin associated glycoprotein delta sarcoglycan antibody
LGMD2F antibody
MGC22567 antibody
Placental delta sarcoglycan antibody
Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) antibody
SG delta antibody
SGCD antibody
SGCD_HUMAN antibody
SGCDP antibody
SGD antibody

Accession NoSwiss-Prot#:Q92629

Uniprot Q92629

Gene ID 6444;

Calculated MW35 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200

IP: 1:10-1:50
Western blot analysis of delta Sarcoglycan on human lung cells lysates using anti- delta Sarcoglycan antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti- delta Sarcoglycan antibody. Counter stained with hematoxylin.

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder. Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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