Product Detail
Product NameCD18 Rabbit mAb
Clone No.JM71-31
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IP
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Names95 subunit beta antibody
Beta 2 (antigen CD18 (p95) antibody
CD 18 antibody
CD18 antibody
Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody
Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody
Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody
Complement component 3 receptor 3 and 4 subunit antibody
Complement receptor C3 beta subunit antibody
Complement receptor C3 subunit beta antibody
Integrin beta 2 antibody
Integrin beta chain beta 2 antibody
Integrin beta-2 (ITGB2) antibody
Integrin beta-2 antibody
Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody
ITB2_HUMAN antibody
ITGB2 antibody
LAD antibody
LCAMB antibody
Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody
Leukocyte cell adhesion molecule CD18 antibody
LFA 1 antibody
LFA1 antibody
Lymphocyte function associated antigen 1 (LFA1) antibody
Lymphocyte function associated antigen 1 antibody
MAC 1 antibody
MAC1 antibody
Macrophage antigen 1 (mac1) beta antibody
MF17 antibody
MFI7 antibody
OTTHUMP00000115278 antibody
OTTHUMP00000115279 antibody
OTTHUMP00000115280 antibody
OTTHUMP00000115281 antibody
OTTHUMP00000115282 antibody
Accession NoSwiss-Prot#:P05107
Uniprot
P05107
Gene ID
3689;
Calculated MW95 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
IP: 1:10-1:50
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
If you have published an article using product 49507, please notify us so that we can cite your literature.
Yes
