Product Detail
Product Namegamma Sarcoglycan Rabbit mAb
Clone No.JA11-57
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IP, IHC
Species ReactivityHu, Ms
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Names35 kDa dystrophin associated glycoprotein antibody
35 kDa dystrophin-associated glycoprotein antibody
35DAG antibody
35kD dystrophin associated glycoprotein antibody
35kDa dystrophin-associated glycoprotein antibody
A4 antibody
DAGA4 antibody
DMDA antibody
DMDA1 antibody
Gamma SG antibody
Gamma-sarcoglycan antibody
Gamma-SG antibody
LGMD2C antibody
MAM antibody
MGC130048 antibody
Sarcoglycan gamma antibody
SCARMD2 antibody
SCG3 antibody
SGCG antibody
SGCG_HUMAN antibody
TYPE antibody
Accession NoSwiss-Prot#:Q13326
Uniprot
Q13326
Gene ID
6445;
Calculated MW32 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200
IP: 1:50-1:100
Western blot analysis of gamma Sarcoglycan on human skeletal muscle cells lysates using anti- gamma Sarcoglycan antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-gamma Sarcoglycan antibody. Counter stained with hematoxylin.
The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
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