Product Detail
Product NameEGF Rabbit mAb
Clone No.JA14-15
Host SpeciesRecombinant Rabbit
Clonality Monoclonal
PurificationProA affinity purified
ApplicationsWB, IHC, IP
Species ReactivityHu
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other NamesBeta urogastrone antibody
beta-urogastrone antibody
EGF antibody
EGF_HUMAN antibody
Epidermal growth factor antibody
HOMG4 antibody
OTTHUMP00000219721 antibody
OTTHUMP00000219722 antibody
Pro epidermal growth factor antibody
URG antibody
Urogastrone antibody
Accession NoSwiss-Prot#:P01133
Uniprot
P01133
Gene ID
1950;
Calculated MW130/10 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1,000
IHC: 1:50-1:100
IP: 1:10-1:50
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-EGF antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-EGF antibody. Counter stained with hematoxylin.
Epidermal growth factor (EGF) is an acid- and heat-stable 53 amino acid protein originally found in rodents and humans. It has been shown to be a potent mitogen for a variety of cell types both in vivo and in vitro. EGF binds to the EGF receptor on the surface of cells and mediates intrinsic phosphorylation of the receptor on tyrosine residues. It has been detected in nearly all body fluids, such as urine (urogastrone), saliva, milk and platelet-rich plasma. EGF, TGFα and vaccinia virus growth factor exhibit 30-40% amino acid homology. Several additional members of the EGF/TGF family have been described; these include Cripto, Amphiregulin and the heparin-binding EGF-like growth factor. Amphiregulin and the heparin-binding EGF-like growth factor both bind to the EGF receptor.
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